Here is a list of some very popular plugins that not only allows you to easily insert ads into your posts, pages and sidebars but also provide rotation capabilities, tracking and more. All these plugins are WordPress 3.0 compatible.
AdRotate – One of the most popular ( 106,075 downloads to-date , rated 4+ stars ) ad management plugins. AdRotate enables you to add and manage ads from a dedicated dashboard. You can chose to show a random banner, or multiple banners .It supports unlimited groups for banners allowing to tie certain banners to different areas of the website.
Advertising Manager – Another popular ( 292,950 downloads to-date , rated 4- stars ) ad management plugin, it manages and rotates your Google Adsense and other ads . The plugin automatically recognises many ad networks including Google Adsense, Adify, AdGridWork, Adpinion, Adroll, Commission Junction, CrispAds, ShoppingAds, AdBrite, Chitika and more.
Quick Adsense – A plugin that allows you to include AdSense and other affiliate code. One of the unique features it offers is the ability to place ads randomly within a post which is a good way to experiment a variety of ads formats & placements. ( 100,848 downloads to-date , rated 4.5 stars )
AdSense Integrator – This plugin enables you to create different ad blocks and place them within your theme or individual posts. It is compatible with the latest Google rules and AdSense updates. It can also be used with other ad networks like AdBrite, Oxado, AffiliateBOT, Share A Sale, LinkShare, Commission Junction and more. ( 79,316 downloads to-date , rated 4- stars )